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alfa/beta ratios for human normal tissues and tumours |
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Written by Willy Gerber
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Monday, 16 June 2008 21:26 |
| Tissue/organ | End Point | α/β ratio (Gy) | 95% conf. lim.[Gy] | Reference | | Early reactions | | Skin | Erythema | 8.8 | [6.9;11.6] | Turesson and Thames (1989) | | | Erythema | 12.3 | [1.8;22.8] | Bentzen et.al. (1988) | | | Desquamation | 11.2 | [8.5;17.6] | Turesson and Thames (1989) | | Oral mucosa | Mucositis | 9.3 | [5.8;17.9] | Denham et.al.(1995) | | | Mucositis | 15 | [-15;45] | Rezvani et.al. (1991) | | | Mucositis | ~8 | ? | Chogule and Supe (1993) | | Late reactions | | Skin/vasculature | Telangiectasia | 2.8 | [1.7;3.8] | Turesson and Thames (1989) | | | Telangiectasia | 2.6 | [2.2;3.3] | Bentzen et.al. (1990) | | | Telangiectasia | 2.8 | [-0.1;8.1] | Bentzen and Overgaard (1991) | | Subcutis | Fibrosis | 1.7 | [0.6;2.6] | Bentzen and Overgaard (1991) | | Muscle/vasculature/cartilage | Impaired shoulder movement | 3.5 | [0.7;6.2] | Bentzen et.al. (1989) | | Nerve | Brachial plexopathy | <3.5 | ? | Olsen et.al. (1990) | | | Brachial plexopathy | ~2 | ? | Powell et.al. (1990) | | | Optic neuropathy | 1.6 | [-7;6.2] | Jiang et.al. (1994) | | Spinal cord | Myelopathy | <3.3 | ? | Dische et.al. (1981) | | Eye | Corneal injury | 2.9 | [-4;10] | Jiang et.al. (1994) | | Bowel | Stricture/perforation | 3.9 | [2.5;5.3] | Deore et.al. (1993) | | | Various late effects | 4.3 | [2.2;9.6] | Dische et.al. (1999) | | Lung | Pneumonitis | 4.0 | [2.2;5.8] | Bentzen et.al. (2000) | | | Lung fibrosis (radiological) | 3.1 | [-0.2;8.5] | Dubray et.al. (1995) | | Head and neck | Various late effects | 3.5 | [1.1;5.9] | Rezvani et.al. (1991) | | | Various late effects | 4.0 | [3.3;5.0] | Stuschke and Thames (1999) | | Supraglottic larynx | Various late effects | 3.8 | [0.8;14] | Maciejewski et.al. (1986) | | Oral cavity + oroph. | Various late effects | 0.8 | [-0.6;2.5] | Maciejewski et.al. (1990) | | Tumour | | Head and Neck | | | | | | - Larynx | | 14.5 | [4.9;24] | Rezvani et.al. (1993) | | - Vocal cord | | ~13 | Wide | Robertson et.al. (1993) | | - Oropharynx | | ~16 | ? | Horiot et.al. (1992) | | - Buccal mucosa | | 6.6 | [2.9;infinity] | Maciejewski et.al. (1989) | | - Tonsil | | 7.2 | [3.6;infinity] | Maciejewski et.al. (1989) | | - Nasopharynx | | 16 | [-11;43] | Lee et.al. (1995) | | - Various | | 10.5 | [6.5;29] | Stuschke and Thames (1999) | | Skin | | 8.5 | [4.5;11.3] | Trott et.al. (1984) | | Prostate | | ? | | Brenner and Hall (1999) | | Melanoma | | 0.6 | [-1.1;2.5] | Bentzen et.al. (1989) | | Liposarcoma | | 0.4 | [-1.4;5.4] | Thames and Suit (1986) | From Basic Clinic Radiobiology, G.Gordon Steel Copyright gPhysics.net
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